API-first chemical compliance index

Search our index of chemical substances and their regulatory compliance status across major frameworks — by name, CAS, InChIKey, SMILES or PubChem CID.

123,803,944 molecules·6 jurisdictions·185,427 compliance entries

Pharma

Active ingredients & excipients across REACH, CLP and FDA/EMA approvals.

Food

Additives, food-contact materials and residue limits for ingredients & packaging.

Cosmetics

Restricted & banned substances across CLP, Prop 65 and cosmetics rules.

[PRODUCTS]

Two ways to use the index

[API]

Compliance API

Resolve any substance and read its regulatory status across every framework — programmatically.

  • Lookup by name, CAS, InChIKey, SMILES or PubChem CID
  • Coverage across REACH, CLP, TSCA, Prop 65, PFAS, FDA & EMA and more
  • JSON responses, API keys and usage quotas

[MONITORING]

Ongoing monitoring

Watch the substances that matter to you and get alerted the moment their status changes.

  • Build watchlists of substances or whole portfolios
  • Alerts on new listings, restrictions and delistings
  • Backed by our tracked regulatory change history